Medigene AG (MDG1, Frankfurt, Prime Standard, TecDAX) announces that a scientific article on a method to identify T cell receptors (TCRs) specific for novel and immunodominant peptide-MHC (pMHC) targets for use in TCR immunotherapy has been published in "Human Gene Therapy" (DOI: 10.1089/hum.2017.122). The research results show how a platform like Medigene's also serves to identify TCRs against oncogenic viruses like the human papillomavirus (HPV16).
TCR immunotherapy uses T cells modified to express new TCRs to enable detection and killing of cancer cells. Efficacy of TCR immunotherapy depends on targeting antigenic peptides that are efficiently presented by the best suited
TCR immunotherapy uses T cells modified to express new TCRs to enable detection and killing of cancer cells. Efficacy of TCR immunotherapy depends on targeting antigenic peptides that are efficiently presented by the best suited
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