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Spermienmigration im Genitaltrakt - Computersimulationen identifizieren Schlüsselfaktoren für den Reproduktionserfolg

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Ein Forschungsteam der Humboldt-Universität zu Berlin und des Leibniz-Instituts für Zoo- und Wildtierforschung (Leibniz-IZW) hat ein Agenten-basiertes Computermodell entwickelt, um die Passage von Spermien durch den weiblichen Genitaltrakt zu simulieren. Damit konnten Schlüsselfaktoren für den erfolgreichen Transit der männlichen Keimzellen ohne den Einsatz von Tierversuchen identifiziert werden. Die Ergebnisse wurden in der Fachzeitschrift „PLoS Computational Biology“ veröffentlicht.

Bei einer Paarung von Wildtieren überträgt ein Männchen Millionen von Spermien in den weiblichen Fortpflanzungstrakt. Auf dem Weg zur Eizelle müssen die Spermien den weiblichen Genitaltrakt passieren. Bei dieser Passage sinkt die Anzahl der Spermienzellen, die weiterkommen, dramatisch ab, nur wenige kommen in
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