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Forschungsverbund Berlin e.V. Rudower Chaussee 17 12489 Berlin, Germany http://ww.fv-berlin.de
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Forschungsverbund Berlin e.V.

Kennst du deine Nachbarn? Fortschritte in der Wildtier-Genomforschung durch eine neue molekulare Methode

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Einem Team von Wissenschaftler*innen des Leibniz-Instituts für Zoo- und Wildtierforschung (Leibniz IZW), des Australischen Museums und des Max-Delbrück-Centrums für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC) ist es gelungen, eine neue Methode zur Identifizierung beliebiger flankierender Gensequenzen zu entwickeln. Bislang verwendete Ansätze, unbekannte Erbgut-Sequenzen neben kleinen bekannten Fragmenten zu bestimmen, sind fehleranfällig. Die Sequenzierung des gesamten Genoms kann eine Lösung sein, ist aber sehr kostenintensiv. Bei der „Sonication Inverse PCR“ (SIP) wird das Genom durch Ultraschallwellen nach dem Zufallsprinzip fragmentiert und die Fragmente mittels Hochdurchsatzsequenzierung der neuesten Generation entschlüsselt. Die Methode kann zur Charakterisierung jeder DNS-Sequenz (in der Nachbarschaft zu einer
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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.