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Deutsche Forschungsgemeinschaft e.V. Kennedyallee 40 53175 Bonn, Germany http://www.dfg.de
Contact Ms Dr. Dorette Breitkreuz
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Deutsche Forschungsgemeinschaft e.V.

Priority Programme 1365 "The Regulatory and Functional Network of Ubiquitin Family Proteins"

2nd Call for Proposals

(PresseBox) (Bonn, )
Ubiquitin (Ub) has classically been associated with protein degradation via the 26S proteasome. However, in the past decade various nonproteolytic functions of Ub have been elucidated. Additionally, the discovery and investigation of Ub family proteins (UbF) proteins, such as SUMO, NEDD8, FAT10 or ISG15, the majority of which do not primarily function as signals for proteasomal degradation, have provided important new insights in our understanding of cellular key processes, such as signal transduction, DNA repair, transcriptional regulation or protein trafficking. The coordinated investigation of the regulatory and functional network of UbF proteins is the major aim of the UbF Priority
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