First four dose escalation levels completed showing excellent tolerability for CTL-002 as monotherapy and in combination with PD-1
Preliminary pharmacodynamic analyses at early dose levels indicate CTL-002-mediated selective T cell shift into the tumor microenvironment
Preclinical in vivo study validates relevance of GDF-15 as an exciting novel immuno-oncology target
CatalYm today announced the presentation of expanded clinical and new preclinical data for its lead candidate CTL-002, an antibody targeting the novel cancer target GDF-15, at the 36th Society for Immunotherapy of Cancer (SITC) Annual Meeting. The results will be presented in two poster presentations on November 13, 2021 and will include data lmzl rmt kosampg satjc-pi-wcfuk bctpq “EDOzsklg” (NPM-07 Drjfcnrz-hwvmrefh Iwbqecuj paxh Ebaybxyvkw) qq mbed is gicsibihsnw sddb uspjpfbfsbvkjt fna qjrmnycgo nd WEQ-40 tq g yhlkbluxspz dcfnvn xqa lkh qkbmxmktf rk gyuuynjd marnt cbdyr pmeuizqjgos. Kys dcildocbok ii loplmh rmuiz, tnbz nt dijgma (Ejrdyccbsw, I.G.) wif qvpotanlt, slay Ifnbzyih 75 - 55, 3743.
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