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PlasmidFactory GmbH & Co. KG Meisenstr. 96 33607 Bielefeld, Germany http://www.plasmidFactory.com
Contact Ms Janine Conde Lopez +49 521 2997356
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PlasmidFactory GmbH & Co. KG

PlasmidFactory and Evotec agree to collaborate in the area of AAV manufacture

(PresseBox) (Bielefeld, )
The Hamburg biotech company Evotec AG and PlasmidFactory, located in Bielefeld, have now signed an agreement by which the pDG/pDP plasmids manufactured by PlasmidFactory will be used in the platform established by Evotec for the manufacture of AAVs.
For some years now PlasmidFactory has had an exclusive, worldwide licence from the German Cancer Research Centre, Heidelberg (DKFZ), for the manufacture, distribution and use of the helper & packaging plasmids of the pDG and pDP family. These are used in a 2-plasmid system to manufacture adeno-associated viruses (AAVs). This means only two components are needed: a plasmid with the gene to be transferred and the corresponding pDG/pDP plasmid, which contains all the information for the propagation and packaging of AAVs (the so-called “helper & packaging” functions). The production process for AAV vectors, whose use in gene therapy is increasing significantly, is thereby considerably simplified compared to older systems with three plasmids. The plasmids of the pDG/pDP families are available from PlasmidFactory in various serotypes in corresponding quality grades for research purposes up through AAV production in compliance with GMP.
The plasmids manufactured by PlasmidFactory are used by Evotec to produce recombinant AAV vectors for research purposes, especially in the field of neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntington’s diseases. Priority is given to the validation of therapeutic targets and the development of cellular test models for the identification of new control structures (agent identification and development).

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PlasmidFactory GmbH & Co. KG

About PlasmidFactory GmbH & Co. KG:
PlasmidFactory frees scientists from everyday routine tasks.
The company’s laboratories manufacture high-quality plasmid and minicircle DNA according to the individual requirements of its clients.
Our In Stock products supplement our product portfolio. These products are always available and are usually delivered within 48 hours of ordering. They include various plasmids and minicircles with reporter genes (GFP, luc, lacZ), pDG plasmids for AAV virus production and pEPI plasmids with S/MAR elements, which make long-term expression possible.
PlasmidFactory’s research and development department and its complete service department are located in Bielefeld, Germany. Through various projects, sponsored by the Federal Ministry of Education and Research (BMBF) and the Federal Ministry of Economics and Technology (BMWi), and through its partnership with the European excellence network, CINIGENE, PlasmidFactory is the driving force in the development of gene vectors for gene therapy and genetic vaccination. The company researches and works in close cooperation with many renowned institutions such as the German Cancer Research Center (DFKZ) in Heidelberg, the University of Munich, the Charité in Berlin and the Institut Pasteur, to name but a few.


About Evotec AG:
Evotec is a drug research and development company which is rapidly advancing innovative approaches to the development of new pharmaceutical products through research alliances and development partnerships with leading pharmaceutical and biotechnology companies. The company operates worldwide and offers its clients high-quality, stand-alone and integrated solutions in the field of drug discovery, covering all activities from target to clinical development. Bringing together first-class scientists and the latest technologies as well as extensive experience and expertise in key therapeutic areas such as neurology, pain, metabolic disorders, oncology and inflammatory diseases has put Evotec in a unique market position.
Evotec is one of the leading providers in the field of drug discovery, building on knowledge accumulated over more than 15 years. The company has its headquarters in Hamburg, Germany, with additional major operations based in Abingdon in the UK, Göttingen and Munich in Germany, Thane in India and San Francisco in the USA.

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The publisher indicated in each case is solely responsible for the press releases above, the event or job offer displayed, and the image and sound material used (see company info when clicking on image/message title or company info right column). As a rule, the publisher is also the author of the press releases and the attached image, sound and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.