Plasmid DNA for the most exacting requirements

New production facility successfully put into operation

Bielefeld, (PresseBox) - PlasmidFactory's new facility for the production of high purity plasmid DNA is now operating successfully in new, modern labs. Plasmid DNA of the highest quality is being produced in the new premises in accordance with the EMEA guideline CHMP/BWP/2458/03. To ensure product safety, substances of animal origin are not used at any stage of the entire process, guaranteeing maximum possible product purity by reliable exclusion of contaminants such as bacterial chromosomal DNA or damaged plasmids. Only one plasmid is produced in each area - different plasmids are not produced in parallel in the same area.

"High Quality Grade plasmid DNA is produced in our facility based on PlasmidFactory's research cell bank (RCB) and the very effective, patented 'ccc' Grade DNA technology” Dr. Martin Schleef, CEO of PlasmidFactory explains. PlasmidFactory applies a number of quality controls both to the cell bank and to the plasmid DNA product, so that the final result is a product designed especially for your application and that complies with the appropriate regulatory standards. Amongst other applications, PlasmidFactory´s High Quality Grade plasmid DNA is used in the GMP-compliant production of recombinant viruses, antibodies and RNA for clinical trials.

PlasmidFactory GmbH & Co. KG

PlasmidFactory is relieving the scientist of the daily routine tasks. In its laboratories the company is producing high-quality plasmid DNA and minicircle DNA meeting the individual requirements of the research scientist.

Besides contract manufacturing of plasmids and minicircle DNA, PlasmidFactory is also offering gene-synthesis and gene-optimisation. The so-called 'In Stock products' are complementing the product portfolio: these plasmids are always in stock and are usually shipped within 48 hours of order. Presently the following In Stock products are available: various reporter-gene plasmids, pDG plasmids for the AAV virus production, pEPito- and pEPI plasmids with S/MAR elements.

PlasmidFactory's research and development as well as its complete service branches are based in Germany. With various projects sponsored by the German Federal Ministry of Education and Research (BMBF) plus European research co-operations, PlasmidFactory is the driving force in the development of gene vectors. Respectively the company is working in close co-operation with many renowned institutions such as the German Cancer Research Institute (DKFZ) in Heidelberg, the University of Munich, the Charité Berlin and the Institut Pasteur Paris, to name just a few.

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