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TransMIT Gesellschaft für Technologietransfer mbH Kerkrader Straße 3 35394 Gießen, Germany http://www.transmit.de
Contact Dr. Peter Stumpf +49 641 9436412
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TransMIT Gesellschaft für Technologietransfer mbH

TransMIT-Patent für Alzheimer-Wirkstoff erweist sich als äußerst viel versprechend

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Der 2002 von der Gießener TransMIT GmbH zum Patent angemeldete Wirkstoff des Marburger Professors Dr. Thomas Schrader und seines Düsseldorfer Amtskollegen Dr. Detlev Riesner erweist sich während der in vitro-Testphase an lebenden Nervenzellen als äußerst viel versprechend und soll nun in vivo an transgenen Mäusen getestet werden.

Ein künstliches, am Computer maßgeschneidertes Molekül soll zukünftig die bei Alzheimer- sowie Creutzfeld-Jacob-Erkrankungen und BSE abnormal veränderten Eiweiße an ihrer Verklumpung hindern und so einem Absterben der Neuronen und dem schrittweisen Funktionsverlust des Gehirns entgegenwirken.

Unter Einfluss neurodegenerativer Erkrankungen bilden die betroffenen Eiweißmoleküle ihre ursprünglich vorwiegend ungeordnete Struktur in eine Beta-Faltblatt-Struktur um. Als
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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.