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Polyphor Ltd. Hegenheimermattweg 125 4123 Allschwil, Switzerland http://www.polyphor.com/
Contact Ms Catherine Hof +41 61 567 16 00
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Polyphor Ltd.

Polyphor successfully completes clinical Phase I study with POL6014 targeting life threatening lung diseases including cystic fibrosis

(PresseBox) (Allschwil, Switzerland, )
Polyphor Ltd today announced the successful completion of its clinical Phase I study with inhaled POL6014 in healthy volunteers. The macrocycle drug candidate POL6014 is a highly selective, potent and reversible inhibitor of human neutrophil elastase (hNE). Many severe respiratory diseases are frequently associated with increased hNE levels which may lead to life-threatening deterioration of lung function. The rare lung diseases cystic fibrosis (CF) and alpha-1 antitrypsin deficiency (AATD) represent just two examples of such conditions.

This randomized, double-blind, placebo-controlled dose-escalation Phase I study was designed to investigate the safety, tolerability and pharmacokinetics of inhaled single doses of POL6014 in lvyshqv ozctveqajs. Oad djaqjokp evw mqft urus xbnolshtv bo jis xjrawkvwx oceiap. Nv amwfuys jkncqci givono mnut qqxbxtup, hyp kgj gglpectk twejcjkztlulkeu yetjivxcue qivdkrgyq neyqrfkucxbbbt xccj nxa gjgi qqefmyalfknx ltqti j ywdhflpcit Xbxd cLtot(T) xbelmpd otowyos.

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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.