Polyphor Ltd today announced an agreement with Cystic Fibrosis Foundation Therapeutics Inc. (CFFT), Bethesda, Md., to advance the clinical development of the inhaled elastase inhibitor POL6014 in cystic fibrosis (CF). POL6014 reduces the activity of elastase, an enzyme that destroys lung tissue when it is produced in excess.
Under the terms of the agreement, Polyphor will be awarded up to $3 million. As announced last year, Polyphor initiated a Phase I study of POL6014 in healthy volunteers using a customized Pari eFlow(R) aerosol inhaler. A single ascending dose study in the EU is planned to evaluate the safety and tolerability
Under the terms of the agreement, Polyphor will be awarded up to $3 million. As announced last year, Polyphor initiated a Phase I study of POL6014 in healthy volunteers using a customized Pari eFlow(R) aerosol inhaler. A single ascending dose study in the EU is planned to evaluate the safety and tolerability
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