NOMADS UAB, Lithuania, NOMAD Bioscience’s wholly owned subsidiary, announces publication in the Nature group journal Scientific Reports (Š. Paškevičius, V. Dapkutė, A. Misiūnas, M. Balzaris, P. Thommes, A. Sattar, Y. Gleba and A. Ražanskienė, “Chimeric bacteriocin S5-PmnH engineered by domain swapping efficiently controls Pseudomonas aeruginosa infection in murine keratitis and lung models” Sci Rep. 2022 April 19; 12:5865. doi: 10.1038/s41598-022-09865-8) of a collaborative research paper describing successful engineering of broadly active chimeric bacteriocins by using domain swapping. The best chimeric molecule, Nomad’s lead product candidate, has broader antimicrobial spectra against Pseudomonas aeruginosa than the natural bacteriocins, and it provides an
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