.
- Kombination aus Pelabresib und Ruxolitinib führte zu einer signifikanten Verkleinerung des Milzvolumens, die SVR35-Ansprechrate war fast doppelt so hoch wie bei Placebo plus Ruxolitinib
- Starker positiver Trend bei der Symptomreduktion und doppelt so viele Patienten erreichten sowohl SVR35 als auch TSS50 im Vergleich zu Placebo und Ruxolitinib
- Verbesserung der Anämie, einschließlich höherer Hämoglobin-Ansprechraten, weniger Patienten mit Transfusionsbedarf und weniger Anämie als Nebenwirkung im Vergleich zu Placebo plus Ruxolitinib
- Verbesserung der Knochenmarkfibrose um mindestens einen Grad bei mehr Patienten als im Vergleich zu Placebo plus Ruxolitinib
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- Kombination aus Pelabresib und Ruxolitinib führte zu einer signifikanten Verkleinerung des Milzvolumens, die SVR35-Ansprechrate war fast doppelt so hoch wie bei Placebo plus Ruxolitinib
- Starker positiver Trend bei der Symptomreduktion und doppelt so viele Patienten erreichten sowohl SVR35 als auch TSS50 im Vergleich zu Placebo und Ruxolitinib
- Verbesserung der Anämie, einschließlich höherer Hämoglobin-Ansprechraten, weniger Patienten mit Transfusionsbedarf und weniger Anämie als Nebenwirkung im Vergleich zu Placebo plus Ruxolitinib
- Verbesserung der Knochenmarkfibrose um mindestens einen Grad bei mehr Patienten als im Vergleich zu Placebo plus Ruxolitinib
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