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Medigene AG Lochhamer Str. 11 82152 Planegg/Martinsried, Germany https://www.medigene.de
Contact Ms Julia Hofmann +49 89 2000333301
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Medigene AG

Medigene AG: Announces target and outlines design for its first clinical trial in TCR cancer immunotherapy

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(PresseBox) (Planegg/Martinsried, )
Medigene AG (FSE: MDG1, Prime Standard, TecDAX), today announced details on the Company's first clinical trial with T-cell receptor-modified T cells, planned to start in late 2017. Medigene will use an HLA-A2:01-restricted T-cell receptor (TCR) that targets PRAME, a well characterized tumor antigen. Medigene identified a TCR candidate for this target that demonstrates favorable safety and efficacy in extensive preclinical studies. Data on Medigene's selected TCR candidate will be presented at the upcoming American Association for Cancer Research (AACR) Annual Meeting taking place from April 1-5, in Washington, D.C., USA.

Subject to regulatory approval, Medigene intends to start a combined
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