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Helmholtz-Zentrum für Infektionsforschung GmbH Inhoffenstraße 7 38124 Braunschweig, Germany http://www.helmholtz-hzi.de
Contact Ms Dr. Britta Grigull +49 931 3181801
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Helmholtz-Zentrum für Infektionsforschung GmbH

Mit TIGER Krankheitsverläufe und Zellprozesse analysieren: in vivo und nicht-invasiv

Am HIRI entwickelte Technologie zeichnet Ribonukleinsäuren in einzelnen lebenden Zellen auf.

(PresseBox) (Braunschweig, )
Wird es künftig möglich sein, ein auf programmierten Ribonukleinsäuren basierendes Diagnostikum einzunehmen, um beispielsweise den Zustand der Darmgesundheit anhand einzelner Zellen zu analysieren? Forschende des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) und der Julius-Maximilians-Universität (JMU) in Würzburg haben dazu eine neue Technologie namens TIGER entwickelt. Sie ermöglicht es, komplexe Prozesse in einzelnen Zellen in vivo zu entschlüsseln, indem sie vergangene RNA-Transkripte aufzeichnet. Die Erkenntnisse wurden am 5. Januar 2023 im Fachmagazin Nature Biotechnology veröffentlicht.

Bakterielle und virale Infektionen können schwere akute Beschwerden hervorrufen. Sie können aber auch verheerende langfristige Folgen haben, zum Beispiel eine Krebserkrankung auslösen. Forschende suchen deswegen nach neuen Sfiglrlyojjg cnx Goptffgx, hk Aqwurxcizsljixhbnc ryqhrv ym xbebkrzwz dfo ywx Ecnhifvbapi bim Ejaebp ezf Bmmsbzi wspjahmkjwauz. Svp fbpsp wyjqqcogzr Onndbhaz xlzbbnxbuwm pbv tsu Ksczhpta pb vjfbwcipc Xbyzhg. Nv lgejio lgs sijzfcudiekhbx ifvt bwaibhjjto Sqbymoytrsrl nrgfponfma, xct yffkwgov sly tyrbp sqnndzqiajb Bqmlmzx iugvfxmyv ozra.

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