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Helmholtz-Zentrum für Infektionsforschung GmbH Inhoffenstraße 7 38124 Braunschweig, Germany http://www.helmholtz-hzi.de
Contact Helmholtz-Zentrum für Infektionsforschung +49 531 61811401
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Braunschweiger Wissenschaftler beschreiben neue Möglichkeiten des CRISPR-Cas-Systems

(PresseBox) (Braunschweig, )
Viren können nicht nur den Menschen krank machen, sie befallen auch Bakterien. Diese schützen sich mit einer Art "Immunsystem", das - vereinfacht gesagt - aus einer bestimmten Sequenz im Erbmaterial des Bakteriums und einem dazu passenden Enzym besteht. Es erkennt fremde DNA, die beispielsweise von Viren stammen kann, zerschneidet sie und macht dadurch die Eindringlinge unschädlich. Wissenschaftler am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig konnten jetzt zeigen, dass sich das beteiligte Enzym Cas9 in verschiedenen Bakterienstämmen unabhängig voneinander entwickelt hat - was die biotechnologischen Nutzungsmöglichkeiten des bakteriellen Immunsystems erweitert.

Erst vor wenigen Jahren entdeckt, stößt das Immunsystem mit dem kryptischen
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