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Helmholtz-Zentrum für Infektionsforschung GmbH Inhoffenstraße 7 38124 Braunschweig, Germany http://www.helmholtz-hzi.de
Contact Mr Andreas Fischer +49 531 61811405
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Helmholtz-Zentrum für Infektionsforschung GmbH

HIRI- und JMU-Forscher visualisieren den Kampf zwischen Virus und Wirtszelle

Neu entwickeltes Verfahren macht kürzlich aktivierte Gene innerhalb einzelner Zellen ausfindig

(PresseBox) (Braunschweig, )
Zellen sind mit wirkungsvollen Abwehrmechanismen ausgestattet, um gegen Eindringlinge vorzugehen. Schlacht- und Bauplan sind in den Genen festgeschrieben, die bei einem feindlichen Angriff aktiviert werden müssen. Wissenschaftler des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) in Würzburg, einem Standort des Braunschweiger Helmholtz-Zentrums für Infektionsforschung (HZI), und der Julius-Maximilians-Universität Würzburg entwickelten eine neue Methode namens scSLAM-seq, mit der sich die Aktivität tausender Gene in einzelnen Zellen untersuchen und über einige Stunden präzise verfolgen lässt. Erstmals konnten die Forscher erklären, warum manche Zellen erfolgreich von einem Virus infiziert werden, andere hingegen nicht. Darüber hinaus gewannen sie grundlegend neue Erkenntnisse über die Regulation von Genen. Ogkb Dtlfnwvyhc jeyr qo cgy jkjylaqle Nhyoqxi emt Hbwylfxujnog Fveush gnseouhlmetlnp.

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