Small molecules hit it big - new therapeutic approaches against viruses, bacteria, and cancer

Scientists from the Freie Universität Berlin and the NeuroCure Cluster of Excellence led by biochemist Volker Haucke in collaboration with colleagues from Australia and the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin have developed small molecules that inhibit the internalization of important signalling molecules but also of pathogenic organisms such as the immunodeficiency virus (HIV) and bacteria into cells. These compounds inhibit the function of the cellular scaffold protein clathrin und could thereby serve as a starting point for novel therapeutic approaches for the treatment of cancer, viral or bacterial infections or neurological disorders. These results were published in aom rczecd zzzje lc sul obmgwmdlceq wnelaug Ttxp.

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