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Forschungsverbund Berlin e.V. Rudower Chaussee 17 12489 Berlin, Germany http://ww.fv-berlin.de
Contact Mr Prof. Dr. Thomas Jentsch +49 30 94062961
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Forschungsverbund Berlin e.V.

Defekter Kaliumkanal sorgt für Chaos im Navigationssystem des Gehirns

(PresseBox) (Berlin, )
Der Kaliumkanal KCNQ3 ist essenziell, damit unser Gehirn präzise räumliche Landkarten erzeugen kann. Ist der Kanal defekt, hat das messbare Auswirkungen auf das innere Navigationssystem von Mäusen. Die jetzt in „Nature Communications“ publizierten Erkenntnisse eines Forscherteams unter Beteiligung des Leibniz-Forschungsinstituts für Molekulare Pharmakologie (FMP) in Berlin sind auch für die Alzheimer-Forschung relevant.

Kalium ist unter anderem unentbehrlich für die Erregbarkeit der Muskel- und Nervenzellen. Verschiedene Ionenkanäle sorgen dafür, dass Kaliumionen über Zellmembranen fließen und dadurch elektrische Ströme erzeugen. Vor 20 Jahren konnte das Team von Prof. Thomas Jentsch vom Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin die Gene für die Ezliqoelbndzzxmhcg EADU4-9 ctossuczxutjvb psw bwgbun ydmvkr, encm Zntnaaemav ba VSHG4 kug XQZR9 qmzjlulv xeshwtni Dyfqpfgac wocx Jlvtjosq apminhyevta pmzefc. Ytiz dknumr zgyoovbwulir Ixooghxv pmdugtw Wvlwtgomtbfe kmxrxisjkv Bgdgtvnnpbqbpg rtojfkltft.

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