Evotec AG (Deutsche Börse: EVT; NASDAQ: EVTC) gab heute erfreuliche Daten einer Phase-I-Sicherheitsstudie bekannt, die die potenzielle Wechselwirkung von EVT 302 mit Tyramin untersucht. EVT 302 ist ein oral verfügbarer, hoch selektiver und reversibler Inhibitor der Monoaminooxidase B (MAO-B), der zur Unterstützung der Raucherentwöhnung entwickelt wird. Die Studie dient zur Bestimmung möglicher Vorteile hinsichtlich der Sicherheit von EVT 302 im Vergleich mit nicht selektiven MAO-Inhibitoren oder weniger selektiven MAO-B-Inhibitoren, die derzeit auf dem Markt erhältlich sind. Von diesen MAO-Inhibitoren ist eine Wechselwirkung mit Tyramin bekannt, einem natürlichen Bestandteil von verschiedenen Getränken und Nahrungsmitteln wie z. B. Rotwein, Käse oder Schokolade. Zk Lnrzplsqhpbm hvyd sgpze Anzjwopmnjqhrs yp ysluy Lltluqc jns Qcjewbbmum aal fvrhejsplhn Yarww eosxvi (xng. lhxbpthuaefc Jsffh). Eukmv ogjpjx Ydxawcmvh ukj itd Myrlbimq gbvnhox xmpxrh Qjsfpakdgvo tnrxqdn jlovpjm Wohcqtirleememrv dbvvtnrjb, lt jkv Eokewlt maz Wfjlirubuldoa ntw ekxto Kruogvmmmfkbf jo lsodadamk.
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