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Evolva Holding SA Duggingerstraße 23 4153 Reinach, Switzerland http://www.evolva.com
Contact Dr. Khalid Islam +41 61 417 96 60
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Evolva Holding SA

First Patients Enrolled in Phase II Trial With Intravenous ICLAPRIM in HAP/VAP/HCAP

Progress Of Phase I Programme With ORAL ICLAPRIM/"ROLLING" NDA For Intravenous ICLAPRIM in cSSSI; Electronic Submission Of First Modules Due Before Year-End 2007

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Arpida Ltd (SWX: ARPN) announced today the enrolment and dosing of the first patients in the Phase II clinical study with intravenous iclaprim in the treatment of hospital-acquired pneumonia (HAP) / ventilator-associated pneumonia (VAP) / healthcare-associated pneumonia (HCAP).

In addition, Arpida announced results of a Phase I study with oral iclaprim. The primary aim of the study was to assess the safety and tolerability of single ascending doses of an oral capsule formulation of iclaprim in healthy volunteers.

Moreover, Arpida today announced that the first modules of the New Drug Application (NDA) for intravenous iclaprim in its first indication,
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