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ETH Zürich Rämistrasse 101 8092 Zürich, Switzerland http://www.hk.ethz.ch
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ETH Zürich

Krebszell-Cluster auflösen, um Me-tastasen zu verhindern

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Erfolgreicher Test bei Brustkrebs-Patientinnen: Der Wirkstoff Digoxin, bekannt aus der Herzmedizin, löst Klümpchen von zirkulierenden Brustkrebszellen im Blut auf und reduziert so die Gefahr von Metastasenbildung.

Gewisse Tumortypen bleiben nicht an ihrem Ursprungsort, sondern verbreiten sich im ganzen Körper und bilden Ableger. Denn der Primärtumor gibt laufend Krebszellen ins Blut ab. Diese im Blut zirkulie-renden Tumorzellen (englisch: circulating tumor cells, CTC) können sich zu kleinen Häufchen von bis zu einem Dutzend Zellen zusammenschliessen und sich in anderen Organen einnisten. Dort wachsen die Cluster zu grösseren Tumoren, sogenannten Metastasen. Metastasierende Tumore sind noch im-mer ein grosses medizinisches Problem: Jedes Jahr sterben
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