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How to remove unwanted components from the cell nucleus

(PresseBox) (Heidelberg, )
An international team of scientists has uncovered how cells remove unwanted components from the nucleus following mitosis. The results, published in the journal Nature, stem from a fruitful collaboration between the European Molecular Biology Laboratory in Heidelberg and the Institute of Molecular Biotechnology in Vienna. The press release can be found here.

The organisation of cells into specific compartments is critical for their function. For instance, by separating the nucleus from the cytoplasm, the nuclear envelope prevents premature translation of immature RNAs.

During mitosis, however, the nuclear envelope disassembles, allowing large cytoplasmic components such as ribosomes to mix with nuclear
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