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Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280 69120 Heidelberg, Germany http://www.dkfz.de
Contact Ms Dr. Sibylle Kohlstädt +49 6221 422854
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Deutsches Krebsforschungszentrum

Neuer Ansatz für die personalisierte Therapie von Hirntumoren

(PresseBox) (Heidelberg, )
Wissenschaftlerinnen und Wissenschaftler vom Deutschen Krebsforschungszentrum (DKFZ) und von der ShanghaiTech University haben ein innovatives Verfahren entwickelt, um Hirntumoren individueller Patienten besonders naturnah im Labor nachzubilden. Medikamententests in diesem Modell stimmten sehr gut mit den tatsächlichen Patientenreaktionen überein, was es zu einer wertvollen Methode für die Untersuchung von Therapieansprechen macht.

Tumor-Organoide, also Minitumoren, die aus chirurgischem Material in der Kulturschale herangezogen werden, werden heute in der Krebsforschung vielfältig genutzt. Zahlreiche Forschungsgruppen haben bereits Ansätze entwickelt, um auch Hirntumoren, insbesondere für die sehr aggressiven Glioblastome, im Labor zu kultivieren. Allerdings ist die Komplexität der Tumoren eine große Herausforderung für diese Forschung.
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Zila Coxx Twbs 8521, UWZ: 51.5009/e.ihrf.6511.11.226
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