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Deutsches Elektronen-Synchrotron DESY Notkestraße 85 22607 Hamburg, Germany http://www.desy.de
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Deutsches Elektronen-Synchrotron DESY

DESY-Röntgenquelle enthüllt Angriffsmechanismus von Herpesvirus

Entschlüsselung von molekularem Köder liefert Ansatz für neue Medikamente

(PresseBox) (Hamburg, )
Ein internationales Forscherteam hat mit Hilfe der DESY-Röntgenlichtquelle DORIS III eine wichtige Waffe eines weit verbreiteten Herpesvirus entschlüsselt. Die Untersuchung zeigt, wie das Epstein-Barr-Virus mit einem molekularen Köder die Alarmkette der körpereigenen Immunabwehr lahmlegt. Die Erkenntnisse bieten Ansatzpunkte für die Entwicklung neuer Medikamente, wie die Forscher um Savvas Savvides von der Universität Gent (Belgien) gemeinsam mit Kollegen vom Europäischen Molekularbiologie-Labor EMBL aus Grenoble (Frankreich) und Hamburg im Fachjournal "Nature Structural & Molecular Biology" schreiben.

Das Epstein-Barr-Virus gehört zur Gruppe der Herpesviren und löst unter anderem das Pfeiffersche Drüsenfieber (Mononukleose) aus. Darüber hinaus spielt es bei mindestens einer Krebsart eine
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