Genencor and BRAIN establish a research collaboration for the production of biobased chemicals from renewable feedstock

Frankfurt/Main, (PresseBox) - Genencor, a division of Danisco A/S and BRAIN AG, a leading European industrial biotechnology company, located in Zwingenberg, Germany, join forces in the field of the biobased fermentative production of industrially relevant biochemicals from renewable raw materials.

Genencor will use its extensive capabilities in metabolic pathway engineering and biomanufacturing of industrial bio-products and BRAIN AG's world leading expertise in the fields of metagenomics and screening technologies, to pursue product targets for the chemical industry.

BRAIN will provide Genencor access to these technologies and especially to its vast metagenome resources of some 150 million genes of yet uncultured microorganisms. Enzymes and biosynthetic pathways of interest will then be genetically engineered in microbial production strains for the production of important biochemicals. The products can replace petrochemicals and be used in e.g. biofuels, plastics, rubber, adhesives and cosmetics.

This new collaboration announced today expands upon the successful collaboration first established in 2004, where the two companies joined forces to develop a new enzyme product platform.

For BRAIN, the collaboration is also an important milestone in the company's strategy of further expanding its strategic partnerships with globally successful partners from the biochemical industry, thereby strengthening the industrial network at its disposal and ensuring increased support for future projects.

For Genencor, "the field of innovative biochemicals offers a significant new opportunity for business growth and the strategic application of our core competency in the design and operation of cell factories", explains Dr. Karl Sanford, Vice President Technology Development at Genencor. "BRAIN's capabilities and expertise in metagenomic enzyme discovery fits nicely within our model for open innovation where we look to make the transition from bench to market more effective and efficient."


Metabolic Pathway Engineering
Metabolic pathway engineering is the practice of optimizing genetic and regulatory processes within cells (or micro organisms) to increase the cells' production of a certain substance.

The study of genetic material recovered directly from environmental samples.

BRAIN AG is an industrial "white" biotech company which discovers and develops novel bioactive natural compounds and proprietary enzymes for its partners and customers in the chemical and pharmaceutical industries, as well as the food and cosmetics industries. Currently, BRAIN employs 72 scientists, engineers and technicians. BRAIN has entered into partnerships with BASF, Ciba, Clariant, Evonik Degussa, Henkel, Nutrinova, Sandoz, Schering, Südzucker and Symrise, to name but a few.

Danisco Deutschland GmbH

With a rich and innovative portfolio, Danisco is a world leader in food ingredients, enzymes and bio-based solutions. Using nature's own materials, science and the knowledge of our 9,500 people, we design and deliver bio-based ingredients that meet market demand for healthier and safer products. Danisco's ingredients are used globally in a wide range of industries - from bakery, dairy and beverages to animal feed, laundry detergents and bioethanol - offering functional, economic and environmental benefits. Headquartered in Denmark and operating from more than 120 locations, Danisco's key focus is to become our customers' First choice and a truly market-driven global business. In addition, we have one of the most efficient sugar production platforms in Europe. Find out more at

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