Neue Subgruppenanalyse der Phase-III-Studie ARANOTE zeigte: Darolutamid plus Androgendeprivationstherapie (ADT) verbessert das radiologische progressionsfreie Überleben (rPFS) und andere wichtige klinisch relevante Endpunkte bei Patienten mit hoch- und niedrigvolumigem metastasiertem hormonsensitivem Prostatakrebs (mHSPC) im Vergleich zu Placebo plus ADT / Eine zusätzliche Subgruppenanalyse aus der Phase-III-Studie ARASENS zeigte: Patienten mit mHSPC profitierten altersunabhängig (<75 und ≥75 Jahre) von Darolutamid in Kombination mit ADT und Docetaxel / Eine retrospektive Kohortenanalyse mit Real-World-Daten zeigte: Patienten mit mHSPC unter einer Dreifachtherapie mit Darolutamid in Kombination mit ADT und Docetaxel wiesen im Vergleich zu einer Therapie mit Abirateron plus ADT plus Docetaxel eine geringere Wahrscheinlichkeit
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5. Vutb IB, Zukxed JW, Uwnvwh RD, Godi BM, Vandavc D. Wyfsrlibnc Wvpsmmuwhr-Mmnlauexn Xjjklnos Zsphqb: Qgxawkjich Znhzukg Zcimzkaxk psr Atyrtwaxi. Ui Abj Ycra Ieynv Teye Aauz. 8307 Htt 16;94:146-371. mdehr://gko.hvm/01.2307/uxxa_472340. Zonnbnms: Ckhpvce 0255
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