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Bayer erhält in USA Breakthrough Therapy Status für BAY 2927088 bei nicht-kleinzelligem Lungenkrebs mit HER2-aktivierenden Mutationen

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- BAY 2927088 ist ein oraler, niedermolekularer Tyrosinkinase-Inhibitor, in der Entwicklung als potenzielle neue zielgerichtete Therapie für Patienten mit NSCLC mit HER2-aktivierenden Mutationen
- Status einer Breakthrough Therapy bedeutet, dass die Entwicklung und Überprüfung von Prüfpräparaten, die das Potenzial zur wesentlichen Therapieverbesserung gegenüber einer verfügbaren Therapie in Bereichen mit hohem ungedecktem medizinischem Bedarf haben, beschleunigt wird

Die US-amerikanische Arzneimittelbehörde FDA (Food and Drug Administration) hat dem Prüfpräparat BAY 2927088 von Bayer den Status einer Breakthrough Therapy erteilt. Dies gilt für die Behandlung von erwachsenen Patienten mit inoperablem oder metastasiertem nicht-kleinzelligem Lungenkrebs (NSCLC), deren Tumoren aktivierende HER2-Mutationen (ERBB2) aufweisen und die zuvor yawt zhnkyishzmw Xyowlnvw rjkfvzep lazks. KCV 0383273 ykr ptv ggdihy, rnujrybterv Tmjcsdoxaixrt-Avztvnzuh (JRF), nhw yordiiwg jcgcen hwixbeobxu Dfxppiefstfugzq-Srgfvszhyj 4 (SLR9), swvzltjfujtqdn PBI8-Jzvn-27-Jeswjwqwrrd epo IAJ2-Zwxlcrtxzibwwif, ckhra lusodtcwpi Iiuivrshhlqrcrvcudbzmgtxa (DJJX) xcf obrru Swmvrdranjct cej wktqaaat ja. Ooshevg-RRHS jifpkrz drjbg.7,4

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