Klinische Wirksamkeit für alle Asunercept-Dosisgruppen nachgewiesen
Statistisch signifikant schnellere klinische Genesung für kombinierte Behandlungsgruppen im Vergleich zur Kontrollgruppe
Exzellentes Sicherheitsprofil von Asunercept bestätigt
Phase-III-Zulassungsstudie eingeleitet
Apogenix, ein biopharmazeutisches Unternehmen, das Immuntherapeutika der nächsten Generation entwickelt, gab heute bekannt, dass Asunercept in der ASUNCTIS-Studie statistisch signifikante Vorteile für hospitalisierte COVID-19-Patienten zeigte. Die offene, multizentrische Phase-II-Studie untersuchte die Wirksamkeit und Sicherheit von Asunercept bei 435 Patienten mit mittelschwerer bis schwerer COVID-19-Erkrankung. COVID-19-Patienten wurden im Verhältnis 1:1:1:1 in vier Studienarme randomisiert und erhielten 25, 100 oder 400 mg Asunercept (einmal wöchentlich, i.v.) zusätzlich zur Standardtherapie (Standard of Care, SOC) bzw. SOC allein.
Die Wirksamkeit wurde anhand
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tqft Derkngzzju
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