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AMS Biotechnology Europe Ltd Herriotstrasse 1 60528 Frankfurt, Germany http://www.amsbio.com
Contact AMSBIO Germany +49 69 779099
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AMS Biotechnology Europe Ltd

Organoid Biobank zur Vorhersage des Behandlungserfolgs verschiedener Medikamente an Krebspatienten

(PresseBox) (Frankfurt, )
AMSBIO berichtet von einer Studie, veröffentlicht in Cell (1), welche die Fähigkeit von Organoiden zeigt, dreidimensional die vielfältigen Mutationen, die in Tumoren vorkommen, einzufangen. Organoide sind kleine Zellansammlungen, die akkurat das Verhalten von menschlichem Gewebe nachahmen und zum Testen von Krebs-Medikamenten verwendet werden können. Auf lange Sicht ermöglichen sie das Erkennen effektiver personalisierter Behandlungen für Patienten.

In der beschriebenen Forschungsarbeit wurden 20 Patienten mit kolorektalen Karzinomen Proben von gesundem und krebsartigem Gewebe entnommen und zur Produktion von Organoiden verwendet. Diese Organoide wurden anschließend einer Reihe von Medikamenten für kolorektalen Krebs in Form von Hochdurchsatz-Screening ausgesetzt, welches Hunderte von Medikamenten an Jgzkv-Nrsdmuaogw qwlfrc.

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