Following previous International Conferences on Laser Applications in Life Sciences (LALS), e.g. in Oulu, Taipei or Moscow, it is now our pleasure to invite you for LALS-2014 which will take place from June 29 th to July 2 nd in \"Edwin Scharff Haus\" conferences center at Ulm/Neu Ulm (Germany) on the banks of the Danube river. Here we will bring leading scientists in the fields of Biomedical Imaging, Laser spectroscopy, Laser- Tissue Interactions, Light Microscopy and Novel Optical Devices together in a stimulating atmosphere. Ulm is not only the city with the highest cathedral of the world and the native town of Albert Einstein, but it has always been a centre of trade with many states along the Danube as well as all over the world. Its warm atmosphere is most evident during the summer when many beer gardens are open! The conference will be preceded by a German-Russian satellite symposium on Clinical Laser Applications.