Nanion Technologies and Assay.Works partner to offer drug discovery services for membrane transporter targets

Backed by Nanion's electrophysiology expertise, Assay.Works will be providing SURFE²R assays "As-a-Service" / The offering adds an economic, low-risk option for researchers seeking predictive assays for membrane transporters

The SURFE²R (surface electrogenic event reader) technology allows the investigation of electrogenic transporters (symporters, exchangers and uniporters) and pumps. The SURFE²R 96SE instrument is an All-in-one device, including liquid handling, hardware and computer allowing 96 parallel recordings with up to 10,000 data points per day.
(PresseBox) ( München, )
Nanion Technologies, a leading provider of automated electrophysiology systems, today announced the partnership with Assay.Works, experts in assay development and High Throughput Screening (HTS), who will be providing SURFE²R 96SE assays “As-a-Service” for membrane transporter research.

Membrane transport proteins, enabling active and secondary active transport of ions and solutes across the membrane, are important drug targets but may also be involved in unwanted side effects of novel drug candidates. Establishing predictive and scalable assays to identify and characterize bioactive substances for members of this protein family has been challenging and often required the use of radioactivity. Nanion’s SURFE²R platform employs label-free, SSM-based electrophysiology to resolve small currents of transporters and pumps.

To respond to the growing demand in assay options for membrane transporters and to afford researchers access to SSM-based electrophysiology, Nanion and Assay.Works entered into a partnership:

Supported by Nanion’s comprehensive electrophysiology expertise and technical know-how, Assay.Works now offers assay development, proof-of-principle studies, and compound screening on the SURFE²R 96SE which combines the electrophysiology hardware with online liquid-handling, allowing 96 parallel recordings with up to 10,000 data points per day. With extensive experience developing and performing functional assays for challenging targets across indications, Assay.Works is well positioned to help clients jump-starting their membrane transporter programs.

Dr. Maria Barthmes, Product Manager of the SURFE²R instrument family says: “We are delighted to enter into this valuable partnership with Assay.Works. Many of our clients are asking for a trustworthy service partner for their drug discovery efforts on membrane transporter targets. Assay.Works is standing out concerning their long-lasting experience in HTS assay screening, their capabilities, including cell and membrane production, as well as their complementary screening service portfolio.“

Dr. Ralf Schwandner, CEO of Assay.Works, adds: “We are excited to deepen our long-standing relationship with the electrophysiology experts at Nanion. Their SURFE2R platform perfectly fits our mission to develop and apply predictive and scalable assays for therapeutics discovery. Through the partnership with Nanion, our clients pursuing membrane transporter research will benefit from the new assay services we can offer based on the latest SSM-based electrophysiology technology provided by Nanion.“

About Assay.Works:

Assay.Works is a contract research organization (CRO) providing research services to pharmaceutical/biotech companies and academic organizations in form of fee-for-service work.
Our mission is to accelerate our partner's research programs by developing and executing predictive and scalable assays to quantify the bioactivity of novel chemical and biological entities. We combine scientific rigor with our domain expertise in laboratory automation, informatics, and industry best practices to turn challenging assays into quantitative, reproducible results. Assay.Works’ service portfolio includes Assay Development, Cell Line Engineering and Production of Cellular Reagents, Bioactivity Assessments, Quantitative Biology Applications, and High-Throughput Screening (HTS).
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