NGS generates large amounts of data at unprecedented speed at much lower costs than traditional sequencing methods. Though, having a sequencing platform and an analysis software package only will not bring interpretable results ready to be published. This is where MicroDiscovery’s service starts: their interdisciplinary specialists’ knowhow and experience for handling, exploiting, interpreting and visualizing results offers more than software ever could.
The customized service solutions for research include statistical methods that analyze NGS data at all steps from sequencing to results. Reads from raw data from a range of different Next Generation Sequencing platforms can be mapped and mapping statistics generated. Next to that, especially in ChIP-Seq or MeDIP-Seq experiments, specific protein binding regions on DNA can be detected through efficient methods in peak finding and target region characterization. During all phases of analysis, an extensive control on read length, distribution and quality is carried out to overcome bias problems and to be able to come to statistically significant results. Furthermore, all results are graphically visualized on the genome or trancriptome sequence.
Whether research questions concern mutations, such as SNPs, InDels, or CNV, protein binding characteristics, or differentiated expression profiles, MicroDiscovery offers bioinformatics and statistics services that guide you from experimental setup to significant results.