JPK Instruments installs first optical tweezers system in the Netherlands
JPK Instruments has recently installed its NanoTracker™ system, a versatile force-sensing optical tweezers platform. Dr. Remus Dame, an assistant professor of Leiden University in the Netherlands, had worked with home-built optical tweezers instrumentation earlier in his career. With the advent of a commercial system, he is able to carry out his research without the extra worries to design, build and maintain another homemade system.
Optical tweezers are a microscope-based technique that can be used to manipulate molecules or cells with high precision on the nanometer scale. In more advanced ‘force-sensing’ systems, the forces that one exerts can actually be recorded with high precision, too. This approach has been used to study many mechanical aspects of biological systems, such as those involving motor proteins or DNA. However, it has largely been the playground for physicists and biophysicists, who have the expertise to develop such intricate instruments themselves.
Dame has done postdoctoral research in such a biophysics group, resulting in a series of publications in many peer-reviewed scientific journals including Nature (Nature 444:387-390, 2006). With a background in (bio)chemistry, he deliberately did not want to specialize in instrument development while setting up his own lab, but preferred to spend his time on tackling interesting biological questions with the right techniques. For him, the occurrence of off-the-shelf optical tweezers platforms came at the right moment.
Dame will use his JPK NanoTracker™ to continue his research on the physical interaction of DNA and its associated proteins. For him, the availability of ongoing support offered by JPK Instruments, both technically and in terms of applications, provided a strong argument to purchase the NanoTracker system.
For further details, please contact the JPK web site, www.jpk.com
JPK Instruments AG
JPK Instruments AG is a world-leading manufacturer of nanoanalytic instruments - particularly atomic force microscope (AFM) systems and optical tweezers - for a broad range of applications reaching from soft matter physics to nano-optics, from surface chemistry to cell and molecular biology. JPK was recognized as Germany’s fastest growing nanotechnology company in 2007 and 2008 (Deloitte). From its earliest days applying atomic force microscope (AFM) technology, JPK has recognized the opportunities provided by nanotechnology for transforming life sciences and soft matter research. This focus has driven JPK’s success in uniting the worlds of nanotechnology tools and life science applications by offering cutting-edge technology and unique applications expertise. Headquartered in Berlin and with direct operations in Dresden, Cambridge (UK) and Singapore, JPK maintains a global network of distributors and support centers and provides on the spot applications and service support to an ever-growing community of researchers.
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