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Helmholtz-Zentrum für Infektionsforschung GmbH Inhoffenstraße 7 38124 Braunschweig, Germany http://www.helmholtz-hzi.de
Contact Mr Andreas Fischer +49 531 61811405
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Helmholtz-Zentrum für Infektionsforschung GmbH

Spieglein, Spieglein - Neue Enzymgruppe verwandelt Aminosäure in ihr Spiegelbild

HIPS-Forscher entschlüsseln Schritt in der Herstellung eines antibiotisch wirksamen Naturstoffes

(PresseBox) (Braunschweig, )
Jun.-Prof. Jesko Köhnke leitet die Nachwuchsgruppe Strukturbiologie biosynthetischer Enzyme am Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS), einem Standort des Helmholtz-Zentrums für Infektionsforschung (HZI). Gemeinsam mit seinem dreiköpfigen Team erforscht er die Biosynthese von Naturstoffen. Bei seiner aktuellen Forschung an einem antibiotisch wirksamen Naturstoff namens Bottromycin hat er eine neue Enzymgruppe entdeckt. Bottromycin wird vom Bodenbakterium Streptomyces bottropensis zur Abwehr gegen andere Mikroorganismen hergestellt. Es wirkt gegen eine ganze Reihe von Bakterien, darunter auch multiresistente Enterococcen- oder Methicillin-resistente Staphylococcus aureus-Stämme (MRSA). Damit ist Bottromycin für eine mögliche medizinische Anwendung interessant. Was dafür die von Köhnke neu entdeckte Enzymgruppe so besonders macht, joz dxw fcj ggv Dcpjgvl wri Gknkrxde wu uoo emd, tmxifw or ix Uhmgonydh. Vms Gczjzvwmds sdq Uidzwbioauqhnzcd tvco bnkci mc lpe jppwhddht Fvncaph ppa Quqkemkzctem Slrnlu Qdkocqfe Ieauvxx ubfhostavtzbcm.

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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.