Im Neuenheimer Feld 519
69120 Heidelberg, de
+49 (6221) 6510-363
The National Center for Genome Resources Studies Childhood Diseases Using febit's DNA Capture Method
The National Center for Genome Resources (NCGR) has selected febit's DNA-capture method, HybSelectTM, to re-sequence the exons of genes involved in over 400 of the most devastating childhood diseases with the ultimate goal of developing genetic tests to detect carrier status for recessive genetic diseases in prospective parents.
In this collaboration the NCGR will bring its experience in comprehensive Illumina sequencing studies to febit's automated HybSelect technology for targeted re-sequencing to develop and test highly parallel analysis. This will enhance the multiplexing capability of HybSelect to perform surveys in large-cohort studies.
NCGR scientists searched for a fast and affordable technology that would allow them to capture the exons of interest for re-sequencing. febit's automated HybSelect technology for targeted, hybridization-based DNA enrichment supports deep sequencing studies resulting in high coverage results. The Geniom RT Analyzer® provides the easy-to-use and highly automated capturing of the desired DNA fragments for further Next-Generation Sequencing (NGS).
Stephen Kingsmore, CEO of NCGR, stated: "We are impressed by the unique flexibility and scalability of febit's HybSelect technology and with the ease of integration in production sequencing with Illumina Genome Analyzers. In partnership with the Beyond Batten Disease Foundation, we aim to combine these technologies to offer highly cost effective screening for rare childhood diseases."
febit will provide its technology, application, training and support to NCGR. "We are delighted that NCGR will use our flexible Geniom technology to investigate rare genomic diseases," said Peer Staehler, CSO of febit. "The flexible content of the microarray-based biochip allows researchers to fully determine the capture probes and incorporate new results. This cooperation supports febit's progress in developing capable new biomarkers for complex diseases."
NCGR is a non-profit research institute, based in Santa Fe, New Mexico, dedicated to improving human health and nutrition by genome sequencing and analysis.
For more information, please visit www.ncgr.org.
About the Beyond Batten Disease Foundation
BBDF is an organization committed to finding a cure for Batten disease, a rare and fatal neurodegenerative disorder that claims the lives of children. The Foundation is also focused on developing a single, inexpensive blood test to detect the gene mutations for Batten disease and hundreds of rare genetic diseases.
For more information, please visit www.beyondbatten.org.
Die Nutzung von hier veröffentlichten Informationen zur Eigeninformation und redaktionellen Weiterverarbeitung ist in der Regel kostenfrei. Bitte klären Sie vor einer Weiterverwendung urheberrechtliche Fragen mit dem angegebenen Herausgeber. Bei Veröffentlichung senden Sie bitte ein Belegexemplar an firstname.lastname@example.org.