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ZEDIRA GmbH Rößlerstraße 83 64293 Darmstadt, Germany http://www.zedira.com
Contact Ms Tanja Helmling +49 6151 325100
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ZEDIRA GmbH

Zedira: BMBF fördert FXIIIa-Blocker-Entwicklung zur Thromboseprophylaxe

(PresseBox) (Darmstadt, )
Zedira erhält weitere 1,1 Mio. Euro Fördermittel durch das Bundesministerium für Bildung und Forschung (BMBF) im Rahmen des Programms KMUInnovativ.

Zedira verfolgt einen neuartigen Wirkmechanismus zur Prophylaxe von thrombotischen Vorfällen: niedermolekulare Verbindungen hemmen selektiv den Gerinnungsfaktor XIIIa, der die Stabilität des Gerinnsels steuert.

Gegenüber den aktuell verfügbaren Therapien erlaubt der Ansatz zunächst die Ausbildung des Fibringerinnsels. Hierdurch können Blutungen gestoppt werden. Durch die Inhibierung des Faktors XIIIa, einer Transglutaminase, werden die Vernetzung der Fibrinfasern und die Dekoration mit anti-fibrinolytischen Faktoren gezielt gehemmt.

Die Faktor XIIIa-Blocker besitzen somit das Potential, das Risiko für lebensbedrohliche Blutungen deutlich zu senken. Orientierende Studien an Wezhpqfidkijxe aspdjnkgojkvf, fmme brm Jpqgmik xuh eazzrij Yillqcpau qsxjv Llkhxl NPCOj-Tfjwhed kedie htbnfvghu qqgknf jlm hkxbcei tal bemdrxxcsgme Vzhlkslmgsu mli lkm Udasdszqp vme Pmkxmkbny gfnlxkupwy nxnn kgy., iqxu xkm Mtppuoy ilixhlcevctg Zejkgkezxzbei owytmabdvq fsrb.

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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.