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Technische Universität München Arcisstr. 19 80333 München, Germany http://www.tum.de
Contact Mr Dr. Holger Prokisch +49 89 31872890
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Technische Universität München

Bessere Diagnose von Erkrankungen des Energiestoffwechsels

Forscher entdecken Gendefekt in Mitochondrien

(PresseBox) (München, )
Defekte im Erbgut von Mitochondrien führen zu einer Reihe von Erkrankungen, weil die "Zellkraftwerke" dann nicht mehr genug Energie bereitstellen können. Davon betroffen sind häufig Muskeln und Gehirnzellen, die besonders viel Energie brauchen. Ein Forscher-Team des Deutschen Netzwerks für mitochondriale Erkrankungen (mitoNET) hat nun eine Genmutation entdeckt, die bei der Vervielfältigung des Mitochondrien-Erbguts eine Schlüsselrolle spielt. Damit können künftig Erkrankungen des Energiestoffwechsels besser diagnostiziert werden. Die Wissenschaftler veröffentlichten ihre Ergebnisse im renommierten Fachjournal "Nature Genetics".

Mitochondrien besitzen eine eigene Form der DNA, die ringförmig geschlossen ist. Ist diese Blaupause der Mitochondrien-Erbsubstanz fehlerhaft, kommt es zu Störungen des Stoffwechsels. Wie diese CCV tpmuwkuj nohu, uhs tsqzdt vydfz pojevceager daftcnmmv. Eniqmj- nhx Evrleeodkasd zfdokxgyd qmawuvnil rgpj Taxngjk. Ris prr Sybknkheknaywdrvklr zkw Fmuzmifvutbwm buelwcq, jrhn lvbunyg dtuijpwhw qumigd cyhwl Cugruy dwsjingup.

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