Compatibility and testing of nested container and closure systems to help pharmaceutical companies manufacture parenteral medicines

Pharmaceutical packaging industry leaders form the Matrix Alliance to help manufacturers speed breakthrough treatments to market

(PresseBox) ( Vancouver, Canada, )
As next-generation drugs require perfectly aligned manufacturing processes and packaging solutions, leading suppliers have announced the creation of the Matrix Alliance. Their mission is to bring to market complete and compelling solutions for aseptic filling, consisting of nest, stopper, cap and filling machinery to accelerate the adoption rate of breakthrough medicines.

The Alliance was formed on the initiative of Vanrx Pharmasystems with inaugural members ARaymond Life, Daikyo Seiko, Datwyler Group, Ompi, Schott AG, Schott Kaisha and SiO2 Medical Products. Each member brings unique knowledge and experience to the Alliance, as well as industry-leading products. As part of the collaboration, members will leverage the testing and certification of their combined offerings. The Alliance is also a forum providing strategic direction, education, and awareness of new aseptic packaging solutions within the membership and to the market.

The companies are collectively focused on pharmaceutical manufacturing and packaging technologies, and have reached an agreement to work in four key areas:

- Testing of new pre-sterilized container and nested closure systems for parenteral (injectable) medicines;
- Ensuring the compatibility of components from different members;
- Driving industry awareness of those solutions;
- Collaborating on industry education regarding new medicine packaging solutions.

"The need for collaboration in this area arises from the increasing sophistication of manufacturing processes and packaging needed for next-generation parenteral pharmaceuticals. Emerging categories of complex, high-value injectable drugs share the need for innovation in fill / finish and packaging. We believe that collaboration will speed the path of new therapies to the market by our customers, the pharmaceutical companies," Alliance members said in a joint statement.

About Vanrx Pharmasystems:
Vanrx Pharmasystems makes the most technologically advanced sterile filling solutions for the pharmaceutical industry. Vanrx fill-finish machines use isolated robotics and machine vision to automate the packaging of injectable drugs into nested vials, syringes or cartridges. The company was founded by pharmaceutical industry veterans to create the systems needed to make the next generation of innovative therapies. For more information, visit www.vanrx.com.

About ARaymond Life:
- The ARaymond Network is a worldwide leader in fastening and assembly solutions for the automotive industry. Its products are used in the manufacture of nearly all vehicle classes, from city cars to luxury limousines. Other key markets are: Truck, Industrial, Energies, Agriculture and Life.
- Headquartered in Grenoble, France, the ARaymond Network is made up of 37 independent enterprises located in Europe, North and South America, Asia and North Africa.
- Established in 1865, the ARaymond Network has been a family-owned business throughout its history. Current CEO Antoine Raymond is the great-great-grandson of founder AlbertPierre Raymond.
- For further information about ARaymond and the history of the company, visit www.araymond.com and www.araymond-150.com.

About Daikyo Seiko Ltd.:
Daikyo Seiko, Ltd. manufactures pharmaceutical packaging and medical device components. It provides rubber closures for lyophilization drugs, infusion products, and liquid and powdered drugs; and ready to sterilize validated components. Daikyo Seiko, Ltd. was formerly known as Daikyo Gomu Seiko, Ltd. and changed its name to Daikyo Seiko, Ltd. in 1993. The company was founded in 1954 and is based in Tokyo, Japan. It has a sales office in Osaka.

About Datwyler Group:
The Datwyler Group is a focused industrial supplier with leading positions in global and regional market segments. With its technological leadership and customised solutions, the Group delivers added value to customers in the markets served. Datwyler concentrates on markets that offer opportunities to create more value and sustain profitable growth. The Technical Components Division is one of Europe's foremost highservice distributors of electronic, ICT and automation components and accessories. The Sealing Solutions Division is a leading supplier of customised sealing solutions to global market segments, such as the health care, automotive, civil engineering and consumer goods sectors. With a total of more than 50 operating companies, sales in over 100 countries and around 6,500 employees, the Datwyler Group generates annual revenue of some CHF 1,200 million. The Group has been listed on the SIX Swiss Exchange since 1986 (security number 3048677).

About Ompi:
Ompi is the Pharmaceutical Systems division of Stevanato Group. With high-quality production plants in Europe (Piombino Dese and Latina in Italy, Bratislava in Slovakia) and plants in Monterrey (Mexico) and in Zhangjiagang (China, near Shanghai), Ompi produces the entire range of glass primary packaging, from the traditional ones as vials and ampoules, to the highvalue ones as syringes and cartridges for auto-injectors and pen-injectors, including sterile and ready to fill syringes, vials and cartridges (Ompi EZ-fill).

About SCHOTT KAISHA:
SCHOTT KAISHA is the leading manufacturer of tubular glass primary packaging in India having completed 25 years in this business. SCHOTT and KAISHA made a 50 / 50 joint venture for its primary packaging activities in India in 2008. With 2600 employees and 2.5 billion pieces per annum, SCHOTT KAISHA supports its customers, with products comprising of AMPOULES, VIALS, GLASS PREFILLED SYRINGES AND CARTRIDGES, both in normal as well as nested solutions.

About SiO2 Medical Products:
SiO2 Medical Products manufactures vials, pre-filled syringes, and cartridges with improved performance and consistency. The company's containers are precision molded from medicalgrade plastics and the inside surface has a thin, transparent silicon-oxide coating system. The containers combine the durability of plastic with the barrier properties of high purity glass.
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