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Paul-Ehrlich-Institut Paul-Ehrlich-Str. 51-59 63225 Langen in Hessen, Germany http://www.pei.de
Contact Ms Brigitte Morgenroth +49 6103 771030
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Paul-Ehrlich-Institut

Erstmals onkolytische Viren zum gezielten Angriff auf Krebsstammzellen erzeugt

(PresseBox) (Langen in Hessen, )
Forschern des Paul-Ehrlich-Instituts ist es gelungen, erstmals onkolytisch wirksame Viren zu erzeugen, die gezielt CD133-positive Krebsstammzellen infizieren und abtöten. In Tierversuchen ließen sich Tumorherde teilweise vollständig beseitigen. Über die Forschungsergebnisse berichtet Cancer Research in seiner Online-Ausgabe vom 04.01.2013.

Tumoren bestehen in der Regel nicht aus einer homogenen Zellpopulation, bei der alle Zellen gleich empfindlich auf die verschiedenen Therapien ansprechen. Vielmehr wird vermutet, dass viele Tumortypen Krebsstammzellen enthalten. Diese sprechen auf Chemo- und Strahlentherapie in der Regel schlecht an und werden für die Entstehung von Metastasen verantwortlich gemacht. Intensiv wird daher nach Möglichkeiten gesucht, diese auch als tumorinitiierende Zellen bezeichneten Zellen ma yigbtsrcxdxlgg rnv fh yhegrjttlmv.

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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.