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Nycomed's Instanyl® is first intranasal fentanyl approved in Europe for managing breakthrough pain in cancer
Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain. Up to 95% of patients with cancer pain experience breakthrough pain of which two-thirds experience inadequate pain control. Untreated breakthrough cancer pain has a profound impact on patients' quality of life.
Instanyl is an intranasally applied fentanyl spray that has been developed by Nycomed. It is the first fast acting nasal opioid approved for the management of breakthrough cancer pain. The approval of Instanyl is based on a comprehensive data package demonstrating the efficacy and good tolerance of this novel treatment.
"We have had a great unmet need in the management of breakthrough cancer pain. With Instanyl, however, we now have a treatment designed to better meet the needs of a patient suffering from breakthrough cancer pain. Instanyl has a fast onset, a short duration, is well tolerated and is easy to use allowing the patients effective control of the pain episodes with minor adverse effects," said Professor Stein Kaasa from Trondheim University Hospital in Norway and Chairman of the Research Network of the European Association for Palliative Care (EAPC-RN).
Kaasa continued: "Instanyl data presented at the 11th Congress of the European Association for Palliative Care in May in Vienna, and fully published soon, demonstrated an onset of pain relief as early as five minutes underlining the clinical benefit this treatment represents to the patients."
Guido Oelkers, Nycomed's Executive Vice President Commercial Operations added: "Instanyl underlines Nycomed's commitment to therapies with clear medical utility. We strongly believe that this product will provide an innovative approach for the half a million patients with cancer suffering from breakthrough pain in Europe."
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