Myconostica's MycAssay(TM) Aspergillus Kit Shows its Sensitivity in Serum
Infection caused by Aspergillus is the leading cause of infectious death in immunocompromised patients with an estimated 10 million people at risk globally each year. Studies have shown that diagnosis of Aspergillus infection followed by antifungal treatment within the first 10 days of infection reduces mortality from 90% to 40% thus highlighting the necessity of rapid diagnostic testing.
Traditional methods used to identify Aspergillus infections are well-documented as being inaccurate, insensitive and slow, with a result taking up to 10 days. Indeed Aspergillus does not usually culture from blood samples. When MycAssay(TM) Aspergillus is combined with a suitable DNA extraction system, a result can be obtained within 3 hours therefore providing a rapid, sensitive and specific alternative to the conventional techniques used to identify Aspergillus infections.
Commenting on these results, Dr. John Thornback, Chief Business Officer of Myconostica, said: "The potential to detect Aspergillus in blood using PCR has been a topic of great interest to clinicians since it opens up the possibility of new screening strategies for the early detection of IA. The authors note that, for the first time a commercial kit is available providing a methodology that is standardised with reagents that are quality controlled and can facilitate the use of PCR serum testing for IA."
Myconostica Ltd, a UK-based medical diagnostic company specialises in rapid molecular diagnostic tests for life-threatening fungal infections. Traditional methods of the detection of fungal infections are well documented as being relatively insensitive and slow. Tests provided by Myconostica aim to allow healthcare professionals to rapidly identify patients infected thus enabling clinicians to prescribe appropriate drug therapy.
Myconostica is developing and commercialising a portfolio of real-time molecular diagnostic tests for life-threatening fungal infections. Over 10 million people are at risk of these infections each year in Europe and North America alone.