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Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch Robert-Rössle-Straße 10 13125 Berlin-Buch, Germany http://www.mdc-berlin.de
Contact Ms Barbara Bachtler +49 30 94063896
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Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch

Neues Schlüsselelement für Entstehung des Burkitt-Lymphoms entdeckt

MDC-Wissenschaftler entwickeln Modell zur Entwicklung neuer Therapien

(PresseBox) (Berlin-Buch, )
Das Burkitt-Lymphom ist ein bösartiger, rasch wachsender Tumor, der aus einer Unterart der weißen Blutzellen, den B-Lymphozyten des Immunsystems, entsteht und häufig innere Organe sowie das Zentrale Nervensystem befällt. Jetzt haben Dr. Sandrine Sander und Prof. Klaus Rajewsky vom Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch ein neues Schlüsselelement identifiziert, das die Immunzellen zu bösartigen Lymphomzellen umfunktioniert. Sie entwickelten ein Mausmodell, das grosse Ähnlichkeit zum Burkitt-Lymphom des Menschen hat und mit dem neue Therapiestrategien zur Behandlung der Erkrankung entwickelt werden können (Cancer Cell, http://dx.doi.org/10.1016/j.ccr.2012.06.012)*.

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