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eleva GmbH Hans-Bunte-Str. 19 79108 Freiburg, Germany http://www.greenovation.com
Contact Ms Manon Bartusel +49 761 470990
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BfArM erteilt Greenovation grünes Licht zum Start der klinischen Phase-I Studie für moss-aGal, dem weltweit ersten in Moos produzierten Medikament

(PresseBox) (Freiburg, )
Greenovation Biotech GmbH gab heute bekannt, dass das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) die Durchführung einer klinischen Phase I Studie für ihren führenden Arzneimittelkandidaten moss-aGal (Agalsidase) genehmigt hat.

Moss-aGal, eine rekombinant hergestellte Form der humanen Alpha-Galaktosidase, wurde als Enzymersatztherapie (ERT) für Patienten mit Morbus Fabry entwickelt.

Unter Verwendung von Greenovations proprietärer BryoTechnologie wird Moos-aGal in Physcomitrella patens exprimiert, wobei der Proteinoberfläche Mannosereste zugefügt werden, welche an Mannoserezeptoren der menschlichen Zellen binden können. Präklinische Studien, die jüngst im Journal of Inherited Metabolic Diseases veröffentlicht wurden, zeigten eine verbesserte Aufnahme des Proteins in die Zielzellen.

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The publisher indicated in each case (see company info by clicking on image/title or company info in the right-hand column) is solely responsible for the stories above, the event or job offer shown and for the image and audio material displayed. As a rule, the publisher is also the author of the texts and the attached image, audio and information material. The use of information published here is generally free of charge for personal information and editorial processing. Please clarify any copyright issues with the stated publisher before further use. In case of publication, please send a specimen copy to service@pressebox.de.