Tamoxifen is an antagonist of the estrogen receptor in breast tissue. It is a selective estrogen-receptor modulator used in the treatment of breast cancer. Tomoxifen act as antagonist in mammary tissue but it act as agonist in other tissues like endometrium. Tamoxifen is indicated for the treatment of metastatic breast cancer in women and men. It is also used in ductal carcinoma treatment.
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Tamoxifen also used in the other treatments like McCune-Albright syndrome, Infertility, Gynecomastia, Angiogenesis, Gene Expression, Riedel’s Thyroiditis.
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