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Otto-Warburg-Medaille für Alexander Varshavsky

GBM verleiht von Elsevier/BBA dotierte Auszeichnung für bahnbrechende Arbeiten zur fundamentalen biologischen Rolle der intrazellulären Proteindegradation

(PresseBox) (Amsterdam, )
Der aus Moskau stammende und seit 1977 in den USA lebende Biochemiker und Genetiker Alexander Varshavsky ist mit der Otto-Warburg-Medaille der deutschen Gesellschaft für Biochemie und Molekularbiologie (GBM) ausgezeichnet worden. Die Medaille gilt als die höchste deutsche Ehrung für Biochemiker und Molekularbiologen.

Mittels genetischer Untersuchungen an Hefen und Zellkulturen höherer Organismen trug Alexander Varshavsky entscheidend dazu bei, die Bedeutung des Ubiquitin-abhängigen intrazellulären Proteinabbaus aufzuklären, der eine zentrale Rolle bei einer Vielzahl regulatorischer Prozesse spielt, wie beispielsweise im Zellzyklus, in der malignen Transformation, der Entzündungsregulation und der Immunantwort.

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