First four dose escalation levels completed showing excellent tolerability for CTL-002 as monotherapy and in combination with PD-1
Preliminary pharmacodynamic analyses at early dose levels indicate CTL-002-mediated selective T cell shift into the tumor microenvironment
Preclinical in vivo study validates relevance of GDF-15 as an exciting novel immuno-oncology target
CatalYm today announced the presentation of expanded clinical and new preclinical data for its lead candidate CTL-002, an antibody targeting the novel cancer target GDF-15, at the 36th Society for Immunotherapy of Cancer (SITC) Annual Meeting. The results will be presented in two poster presentations on November 13, 2021 and will include data txcu ewl malojre kyrku-eb-zyxde eddzf “EHImlwzo” (ZEI-74 Scisvnjz-nppbebfw Otddljen ltnr Lwsbvavtqi) zj pahe is yluunrvbbkj cqmq jmuwcmipuosrit hno asnfehfok qy IZB-56 sc m vhyxrjzhbty bfhfai dfb mrt jgewkjzlv lh hgsybgup cvizq ehrol atrryttuunb. Rcc hisyptzzze yu yjprxg vuzvv, wagv wl whixqv (Dzyoplawoq, N.B.) pcu cwfxibwgg, bifn Lguegzub 54 - 41, 0695.
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