The SoPRanoTM label-free assay platform from PharmaDiagnostics has been certified to work on all BMG LABTECH microplate readers that have a CCD spectrometer. With this label-free assay platform, IC/EC50s and Kds can be determined for biological interactions such as protein-protein or antibody-antigen. Based upon well-known Surface Plasmon Resonance (SPR) technology that has previously only been found in expensive dedicated biosensing equipment, the SoPRanoTM label-free technology uses Localized Surface Plasmon Resonance (LSPR) - active Gold Nano Rods (GNRs) that can detect the binding of molecules to the GNR surface in a concentration dependent manner.
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