Biametrics Launches b-screen® Microarray Screening Device
b-screen® is able to handle different sample types like body fluids (e.g. serum or whole blood) and other relevant complex matrices such as cell culture medium. Kinetic data can be obtained for almost any kind of biomolecular interaction such as for protein/protein, peptide/protein and small molecules/protein.
b-screen® provides a label-free read-out of up to 10,000 spots per square centimeter. It utilizes a precise and automated microfluidics system for incubation of the microarray with the sample of interest. The device can be used with multiple array layouts (highly scalable), uses glass or plastic type substrates and is compatible with almost any common microarray printer. The high-throughput analysis is characterized by a high time resolution (no scanning) at low noise of the optical readout. No fluorescence labels are needed, which leads to assay conditions as close as possible to the in-vivo situation combined with minimal sample pre-treatment and minimized reagent consumption.
"With b-screen® users are able to easily transfer existing microarrays directly into a label-free assay format thus gaining additional information on kinetics and thermodynamics at high precision and reliability," says Günther Proll, Managing Director of Biametrics. "The device allows very low cost high-throughput screening and the applications we have established demonstrate excellent performance and outcome characteristics. We believe b-screen® provides key advantages over current options like surface plasmon resonance (SPR)".
Biametrics will present its b-screen® system at Analytica 2014 in Munich, Germany.
Biametrics GmbH develops and markets label-free analytical system solutions for life science applications. The patented label-free biosensor technology includes innovative detection, surface chemistry and assay development for the time-resolved analysis of any kind of biomolecular interaction. Biametrics has its headquarters in Tübingen, Germany and is a successful spin-off company from the Eberhard-Karls University. Utilizing its innovative technology, Biametrics has developed two product lines tackling the pressing problems in life science labs: Time and money. The b-screen® device is able to handle any standard microarray format and can detect up to 10,000 bimolecular interactions in a single measurement with unmatched performance. The b-portable® device enables for high quality label-free interaction analysis everywhere using a smart and inexpensive technology. In addition to the development of its own products, Biametrics collaborates with market-leading companies and provides R&D services and licenses in the areas of IVD, life-science research, process control, and homeland-security.