AMSilk is developing a novel spider silk-based coating, called BioShield-S1, for silicone breast implants designed to reduce commonly known side effects that are initiated when the immune system reacts to the implants. Preclinical tests conducted jointly with the University of Bayreuth, Germany and the Department of Trauma, Hand, Plastic and Reconstructive Surgery of the University of Wuerzburg, Germany, showed the efficacy of the implant coating. A first test in rats showed that coated silicone implants were accepted much better than implants without silk coating. In particular, capsular fibrosis and inflammation at the tissue border to the coated implants were significantly hbanlla.
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