Traditionell hat es sich als schwierig erwiesen, adultes somatisches Gewebe in vitro zu expandieren, vor allem hinsichtlich der Komplexität der Imitation entsprechender Umgebungssignale in der Kultur. Huch ** und Mitarbeiter haben dieses Problem gelöst und beschreiben neuartige Protokolle für die langfristige (> 1 Jahr) Expansion und genetische Manipulation von adulten Leber- und Pankreaszellen in 3D Organoidkulturen aus Maus- cxr sxwttyhlpyrf Huxfbflu.
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